For the opening of Blend Boutique in Roseburg, we designed a Point of Sale system that integrates with our web-based inventory database. This POS is now also being used at Nic and Mindy's Boutique in Grants Pass, Oregon.
It uses a bar code scanner and an Epson ESC/POS receipt printer (parallel or USB) with attached cash drawer.
We also made an applet to generate sequential barcodes for the stores to apply to their product tags.
The "cash register" interface is very easy to use and there is a training mode built in which allows the cashier to run fake transactions for training purposes.